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Diflucan 50 mg online ). The study was done by researchers at the Department of Preventive Medicine at Aarhus University, and was published recently (3) in the prestigious Dutch journal, BMC Public Health. They reported no evidence that probiotics could counteract the effects of a high-fat diet on colon bacteria. They found no difference in the microbiome composition of mice and people that didn't undergo the diet. The mice on probiotic diet, however, had a significantly higher microbial DNA compared to those on a standard diet. They had "no effect on the size of stomach" as well. The study was performed in germ-free mice so they had no exposure to digestive enzymes, which is very important for colon development. "We did think that probiotics may enhance colonic health in mice on a high-fat diet, as we could detect more bacteria in colonic tissue of mice on a probiotic diet," said Generico de tecta 40 professor Henrik Larsson from the Department of Physiology at Aarhus University, who led the study. "When they were on a standard diet, they were normal, so we worried that if they had a gut microbiota different from what a normal mouse would have, it could predispose them to gut diseases." This is a concern, though, because the mice are genetically quite different from humans and do not have identical gut microbes. A change in microbiota could alter a person's health and cause different diseases. The results could suggest an alternative. "If we can identify the precise gut microbiome before, during and after the high-fat challenge," Larsson said, "that could also allow us to know exactly when and in which parts of the gut microbiota are being altered. Also, identifying specific microbial communities in mice before they go on to a high-fat diet could provide insights for human studies." If the findings of this study were replicated in humans, then it could have potential applications for preventing disease. "If we could determine the specific microbes (in) intestine before they are exposed to a high-fat diet, we could then potentially identify and treat people before that was happening," said Larsson. (Source, Source) Do probiotics help with colon health? In some ways, this is a surprising result – no data were presented of how probiotics influence colon health. work by encouraging the growth of friendly microbes. In addition to the probiotic yogurt, many other types of yogurt are rich in probiotics. Larsson says that he and his team had previously identified an effect of probiotics on the gut microbiota. reason why it didn't work in this study was a problem with measuring gut microbes using specific methods. "We had to use more extreme and less sensitive methods to measure gut bacteria, such as using a metagenomic approach. This time we used a more standard, quantitative approach, and found no difference to other mice on a standard diet," Larsson told CBC News. How does probiotic supplementation work? Researchers have known that some probiotics are good at helping the gut microbiome grow. But they don't have a good understanding of how these beneficial bacteria exert their benefits. In the study, Larsson and his colleagues treated the mice for 5 days with 50 mg of either a prebiotics (dissolved in water) or probiotics (the probiotic yogurt that contain live bacteria). After 5 days, the mice were given a high-fat diet for another 5 days, followed by 2 weeks of probiotic yogurt intake. The mice had no effect on the animals but exhibited different gut microbiota on diet. During the first 5 days, mice on the probiotic yogurt were protected from a very high-fat diet (the at 90% of their calories came from fat). On the diet, one of prebiotic groups had their abundance increased, while the other two had a reduced abundance of certain gut microbes. The results were same on mice that not treated with probiotics. After the diet, mice on probiotic yogurt had a drastically reduced composition of bacteria in their gut compared to what they had on the standard diet. As you might expect, the differences in gut microbiota were correlated to the difference in gut bacterial composition that occurred in mice on a diet high in fat. This indicates that probiotics, specifically ones have a prebiotic effect, may improve your gut and reduce the risk of disease in a number different ways. "We think that probiotics have beneficial effects on gut bacteria and that this protection is maintained with subsequent consumption. This suggests that probiotics work by increasing the numbers of gut bacteria in the intestine." Larsso